BMI1 and nasopharyngeal carcinoma: Briefly, high Bmi-1 expression was detected more often in T3-T4, N2-N3 and stage III-IV NPC biopsies than in T1-T2, N0-N1 and stage I-II samples, respectively (Figure 2A, 2B; Table 2), demonstrating that the gain of Bmi-1 expression is an important feature of advanced NPC.