HMOX2 and neuroblastoma: We also validated RNA levels by RT-qPCR and confirmed upregulation of neuroguidin (NGDN) and NADH:Ubiquinone oxidoreductase core subunit S2 (NDUFS2) and downregulation of HMOX2 and huntingtin (HTT) RNA levels in G3BP1- and G3BP2-depleted NB cells, respectively (Supplementary Figure 3D–3F).