This gene plays a role as oncogene phosphorylating histones and several transcription factors (for example TP53, c-JUN, BANF1, and ATF2) [44,45,46,47] and regulatory proteins controlling cell proliferation and sustaining tumor growth [48], interfering with non-homologous-end joining (NHEJ) DNA repair pathway (such as KAT5) [49]. This evidence concerns the gene JUN and neoplasm.