Therefore, according to international guidelines, treatment options for MpBC are similar to those of invasive ductal or lobular carcinoma of the breast, including: surgery (either mastectomy or breast-conserving lumpectomy), chemotherapy in an adjuvant or neoadjuvant setting, and radiation, depending on the hormonal receptor status and TNM stage at diagnosis [77]. This evidence concerns the gene NR4A1 and breast lobular carcinoma.