In recurrent GBM samples, LRRC15 expression is significantly associated with macrophage markers, including integrin subunit αM (IT-GAM/CD11b) (p < 0.001), allograft inflammatory factor 1 (AIF1) (p < 0.05) and CD68 (p < 0.001) [57]. The gene discussed is AIF1; the disease is glioblastoma.