Total tau protein CSF levels were higher in AD (403.2 ± 182 pg/mL) than psychotic patients (110.3 ± 67) and in dementia patients (333.8 ± 163 pg/mL) than in psychotic patients or MCI patients (184.1 ± 109, Table 2, p < 0.05). The gene discussed is MAPT; the disease is Alzheimer disease.