Interestingly, the IgM content in CSF was also as a non-significant trend higher in MCI patients (0.6 ± 0.4 mg/L) than in dementia patients (0.27 ± 0.22 mg/L) (Table 2, p = 0.04, Bonferroni correction p-level: <0.005). This evidence concerns the gene CD40LG and dementia.