While all mice that received 0.5 mg of this polyclonal antibody succumbed to infection, there was a statistically significant delay in time-to-death or euthanasia compared to mice receiving PBS alone (p = 0.0003) or mice receiving purified IgG derived from Tc bovines not vaccinated with rF1-V (SAB Negative Control, p < 0.0001) (Figure 5). Here, SH3BP5 is linked to infection.