Cellular lamin B1 expression was previously found to associate with telomere and chromosome instability,[48, 49] recruitment of DNA damage repair proteins,[50] and cellular senescence.[51] However, similar to the resilience to deformation, the elevated lamin B1 level reverted with time in our study while the enhanced proliferation could remain in the selected cancer cells for more than 2 months (Figure 3d,e), which suggested the proliferation change here may be independent of the high lamin B1 phenotype. The gene discussed is LMNB1; the disease is cancer.