After the withdrawal of DEX, 3 cases had no recurrence, 1 case developed into LGS and again achieved complete control after resuming DEX, and the other 1 case had sound-sensitive/insensitive myoclonic nodding by accompanied atypical hypsarrhythmia and continued to have seizures despite administering DEX successively combined with ZNS, CLB, and rufinamide, among other agents. The gene discussed is CLYBL; the disease is Hypsarrhythmia.