While the Pkd2fl/fl; Pax8rtTA;TetO-Cre mouse model may best recapitulate adult ADPKD, only one kidney RNA-seq data set was available for this model, and only two kidney RNA-seq data sets were available for Pkhd1-Cre; Pkd2fl/fl. This evidence concerns the gene PKHD1 and autosomal dominant polycystic kidney disease.