ZEB1 and sarcoma: Notably in sarcomas, the combinatorial overexpression of GRHL2, downregulation of ZEB1 and/or over expression of miR‐200 was required to synergistically upregulate epithelial genes, thus inducing a MET‐like phenotype.[106] Our work reinforces the concept that the ZEB1/miR‐200 regulatory loop control the transition between the Mesenchymal‐hybrid (mesenchymal and epithelial) states, and interestingly, epigenetic silencing of ZEB1 was sufficient to upregulate all the individual miR‐200 cluster members.