Genes central to cellular polarity and adhesion, including CDH1 have previously been identified as targets of ZEB1 in alternative models of breast cancer.[17]Microtubule associated protein 7 (MAP7) has been previously implicated in intercellular adhesion of differentiating keratinocytes,[102] and similarly the laminin‐5 subunits LAMB3 and LAMC2 are critical for the epithelial tissue basement membrane and associated epithelial tissue‐level polarization.[103] Interestingly, very few canonical mesenchymal genes showed significantly changes in the SUM159 or MDA‐MB‐231 cell line. The gene discussed is LAMB3; the disease is breast carcinoma.