TGFB1 and immune system disorder: What signaling molecules sense and interpret the strong vs. weak TGF-β signaling for Treg cell stability and Treg-Th17 cell transdifferentiation and how other TGF-β superfamily members are involved in Treg cell stability and Treg-Th17 cell transdifferentiation warrant further investigation to help understand the etiology and to develop treatments for immune diseases.