CDK2AP1 and oral cavity squamous cell carcinoma: To further explore the relevance of CDK2AP1 loss in OSCC progression towards malignancy, we took advantage of a retrospective cohort of primary oral squamous cell carcinoma of the tongue (n = 100) collected between 2007 and 2013 at the Erasmus MC Cancer Institute and encompassing patients that received surgery as the primary form of treatment (Table 1).