In the three terms, 12 proteins (Acat1, Fasn, Acadm, Aldh7a1, Acox1, Echs1, Acaa1b, Pecr, Gk, Acaa2, Hadha, and Cpt2) revealed severity-dependent upregulation (Fig. 5A), whereas four proteins (Acsl1, Cpt1c, Acadvl, and Cd36) revealed severity-dependent downregulation caused by NEC (Fig. 5B). Here, ACAA2 is linked to necrotizing enterocolitis.