EIF4E and metastatic malignant neoplasm in the lymph nodes: Analysis of The Cancer Genome Atlas (TCGA) RNA expression data and clinical case parameters showed that in the group of BC patients with high eIF4E expression, lymph node metastasis occurred in 71.3% of cases, including 244 cases in N1 (22.8%), 81 cases in N2 (7.6%) and 41 cases in N3 (3.8%), while only 17.6% of the low expression group had metastasis, which was statistically significant (P = 0.021) (Table 1).