NEUROD1 and small cell lung carcinoma: Hierarchical clustering analysis based on neuroendocrine markers [30] showed that 51 SCLC cell lines were separated into 3 clusters, and all 3 ecMYC-containing cell lines were partitioned into cluster C2 (Fig. 7A) with high expression of MYC (Fig. 7C) and NEUROD1 (Fig. 7D).