CD4 and gastric cancer: Bai confirmed the overexpression of YTHDF1 in GC and identified that YTHDF1 suppresses the DC-mediated antitumor immune response, indicating a potential role for YTHDF1 in GC treatment.247 In addition, YTHDF1 has been found to be significantly related to CD4-activated memory T cells, monocytes, macrophages, and activated NK cells in breast cancer.