These findings indicate that YTHDF1 affects survival outcomes and immunotherapy responses in breast cancer.248 High expression of YTHDF1 and YTHDF2 was found to be significantly correlated with increased tumor-infiltrating lymphocyte (TIL) density in non-small cell lung cancer (NSCLC), indicating a potential role for these proteins in the TME.249. This evidence concerns the gene YTHDF1 and non-small cell lung carcinoma.