This study shed light on the critical role of METTL1 in altering TME and suggests a novel strategy for rescuing antitumor immunity.267 Another study showed that METTL1-mediated m7G modification enhanced SLUG/SNAIL translation under sublethal heat stress, indicating an essential role for the m7G modification in the recurrence of HCC after insufficient radiofrequency ablation (IRFA). Here, METTL1 is linked to hepatocellular carcinoma.