The presence of SCN5A variants has also been reported in ERS, albeit at a lower diagnostic yield.53,54 In a study of 262 probands with BrS and 104 with ERS, Zhang et al54 identified a 10% yield of pathogenic SCN5A variants in the ERS group compared with 23% for BrS. Here, SCN5A is linked to amelogenesis imperfecta type 1G.