Another important piece of information is that compound heterozygous or homozygote for (αα)JX and (αα)ALT (Table 2) show an intermediate thalassemia phenotype, instead of hydrops fetalis, indicating that the α-globin genes, in cis to the (αα)JX and (αα)ALT deletions, are not completely silenced [16–20]. The gene discussed is GPT; the disease is hydrops fetalis.