reported the beneficial influence of probiotics (Lactobacillus acidophilus, Bifidobacterium lactis, Bifidobacterium bifidum, and Bifidobacterium longum) and selenium co-supplementation on the general score and insulin, homeostasis model of assessment-insulin resistance (HOMA-IR), quantitative insulin sensitivity check index (QUICKI), fasting plasma glucose (FPG), high-sensitivity C-reactive protein (hs-CRP), total antioxidant capacity (TAC), and glutathione (GSH) serum levels in chronic schizophrenia (Jamilian and Ghaderi, 2021). This evidence concerns the gene INS and Insulin resistance.