To explore the role of the lnc-MRPL39-2:1 in NPC progression, we analyzed the differential expression of lnc-MRPL39-2:1 in the NPC tissues and the non-tumor tissues in the Gene Expression Omnibus database (GEO, https://www.ncbi.nlm.nih.gov/geo/). Here, MRPL39 is linked to nasopharyngeal carcinoma.