HK2 and neoplasm: Real-time qPCR analysis of glucose transporter and glycolytic genes in the xenograft tumor tissues showed that ACE2 overexpression suppressed the mRNA levels of SLC2A1, HK2, ENO1, PFKL, LDHA, and PDK1, while inhibition of Mas receptor with A779 restored the expression of glycolytic components (Figure 5E).