In NSCLC, KRAS mutations, especially transversion mutations, were often found in smokers, while EGFR, ALK, ROS1, and RET mutations or translocations might be more common in light smokers or non‐smokers, other alterations such as TP53, NRAS, and MAP2K1 are also more common in smokers.1 This evidence concerns the gene MAP2K1 and non-small cell lung carcinoma.