In NSCLC, KRAS mutations, especially transversion mutations, were often found in smokers, while EGFR, ALK, ROS1, and RET mutations or translocations might be more common in light smokers or non‐smokers, other alterations such as TP53, NRAS, and MAP2K1 are also more common in smokers.1 The gene discussed is ALK; the disease is non-small cell lung carcinoma.