CD4 and tuberculosis: To our knowledge, there is no reported data in literature on CD4+FoxP3+ T-cells or other Tregs in circulation or skin in the context of HIV-positive DRESS, however, it may be that the continued immune activation in both HIV, TB, and DRESS drive expansion of CD4+FoxP3+ T-cell populations, and that this may be occurring in both peripheral blood and the site of disease.