In the analysis with AKI stage 3and/or pulmonary edema as secondary outcomes, it was found that the cumulative incidence rate of CD8+ T cell > 690 × 106 group was higher than that of CD8+ T cell ≤ 690 × 106, the difference was statistically significant (42.3% vs. 11.54%, P < 0.01, see Figure 7). This evidence concerns the gene CD8A and acute kidney injury.