With AKI stage 3 and pulmonary edema as secondary outcomes, the serum levels of CD8+ (OR, 2.69 [95% CI 1.15, 4.88]; P < 0.01), the serum levels of D-dimer (OR, 1.89 [95% CI 0.99, 3.67]; P = 0.021), the serum levels of Lac (OR, 1.51 [95% CI 1.23, 2.21]; P = 0.016) and the serum levels of PCT (OR, 1.19 [95% CI 0.62, 1.53]; P = 0.031) were found to be risk factors. The gene discussed is LCT; the disease is pulmonary edema.