The glycosylation of PDL-1 in the triple negative breast cancer cells was shown to be induced by EGFR signaling-mediated upregulation of β-1,3-N-acetylglucosaminyl transferase (B3GNT3), an enzyme catalyzing the addition of polyLAcNAc repeats to PDL-1. Here, CD274 is linked to triple-negative breast carcinoma.