A forest plot is presented in Supplementary Figure S1 for the hazard ratio of developing AD and other types of dementia between patients receiving angiotensin II–stimulating antihypertensive medications and those receiving angiotensin II–inhibiting antihypertensive medications, indicating a statistically significant difference in the risk of AD, vascular dementia, MCI, other dementia, and total ADRD. This evidence concerns the gene AGT and Alzheimer disease.