A good proportion of the pathways highlighted as significant were related to immune response, such as TGF-β signaling pathway (KEGG:04350), MAPK signaling pathway (KEGG:04010), bacterial infection (KEGG:05135, KEGG:05100), leukocyte migration (KEGG:04670), FoxO signaling pathway (KEGG:04068), cAMP signaling pathway (KEGG:04024) or Hippo signaling pathway (KEGG:04392). The gene discussed is TGFB1; the disease is bacterial infectious disease.