FOXP3 and neoplasm: Compared with this result, in a study of Triple negative breast cancer (TNBC), it was observed that a positive association for FOXP3 rs3761548 homozygous AA was related to TNBC susceptibility, and most of the TNBC patients (83%) have showed a strong staining for FOXP3 protein in the tumor cells, suggesting a positive association of FOXP3 expression with TNBC susceptibility and prognosis 50.