However, in contrast, a previous study which focused on human papillomavirus infection and cervical cancer precursor lesions has suggested that the homozygous genotype of the rs3761548 variants (A/A) may exert a protective role against HPV infection in women, and the rs3761548 variants (A/A) was observed to be related to decreased FOXP3 expression 19. The gene discussed is FOXP3; the disease is cervical cancer.