The activities of liver enzymes (aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP)) in serum were increased in all diabetic mice (Figure 5), indicating hepatic damage and the leaking of enzymes from the tissues into the circulation as an adverse effect of alloxan-induced diabetes. The gene discussed is GPT; the disease is diabetes mellitus.