OCLN and Cowden disease: For children with mild active CD, the OD value of occludin in the terminal ileum and ileocecal mucosa was 0.34 ± 0.10 and 0.41 ± 0.04 in the drug group, 0.46 ± 0.02 and 0.37 ± 0.01 in the short-chain polypeptide plus drug group before treatment.