showed that nine differentially expressed genes (DEGs), TREM1, S100A9, FPR1, NCF2, FCER1G, CCR1, S100A12, MMP9, and IL1RN, were significantly upregulated in PCOS and NAFLD, whereas these DEGs have been demonstrated to be associated with immune and inflammatory responses (121). This evidence concerns the gene MMP9 and polycystic ovary syndrome.