Then, we examined the exhaustion markers, programmed cell death protein 1 (PD-1), lymphocyte activation gene 3 (LAG-3), and T cell immunoglobin and mucin-domain containing-3 (TIM-3) on the surface of TCR-JUN and TCR T cells following tumor antigen stimulation (Supplemental Figure S5). This evidence concerns the gene HAVCR2 and neoplasm.