In patients with TLS, several inflammatory cytokines including C-reactive protein (CRP), IL-6, interferon-γ (IFN-γ), and ferritin levels were persistently elevated from days 5 to 18, and these cytokines showed biphasic lifting-up when compared with those in patients without TLS (Figures 3A–F). The gene discussed is IFNG; the disease is Tumor Lysis Syndrome.