In our in-house cohort of 158 glioma patients, we found that glioma patients with high TANK expression generally had shorter OS and PFS times than patients with low TANK expression by qPCR (PFS, HR=2.37 (143-3.92); OS, HR=2.34 (1.27-4.29); log-rank test P < 0.05, Figures 2I, J). This evidence concerns the gene TANK and central nervous system cancer.