Using exome sequencing, the presence of multifocal FMD was associated to myosin light chain kinase (MYLK – also involved in thoracic aneurysms), dynein cytoplasmic heavy chain 1 (DYNC2H1), sarcomeric protein obscuring (OBSCN), and RNF213 (involved in Moyamoya disease) genes (42). The gene discussed is OBSCN; the disease is Moyamoya disease.