Luu et al. (2020) found that ADAMTS6 is associated with NSCLC by modulating AGR2, a recently discovered oncogene related to p53. The relationship between ADAMTS6 and NSCLC was further described by Lachat et al. (2020) chromatin immunoprecipitation and qRT-PCR analysis showed that ADAMTS6 expression was upregulated more than 60-fold during EMT and was associated with deletion of the promoter H3K27me3. Here, TP53 is linked to non-small cell lung carcinoma.