When compared with the normal group, UGT1A1, NTCP, OCT1, MATE1, MDR1, BSEP, and OATP1A2 in the NAFLD group are significantly decreased by 24.1, 35.3, 30.8, 38.6, 34.3, 43.7, and 33.8% (p < 0.05), respectively. The gene discussed is SLCO1A2; the disease is metabolic dysfunction-associated steatotic liver disease.