Moreover, our results reveal that DHX9 can facilitate cellular proliferation and metastasis in Hep-3B, H1299 and MDA-MB-231 cells via promoting EMT process; however this phenomenon is not observed in renal cancer cells, where DHX9 expression appears to reciprocally suppress the cancerous and EMT pathway, therefore, our results are consistent the previous findings (Gong et al., 2021). This evidence concerns the gene DHX9 and renal carcinoma.