Of these patients, 6 presented diffuse astrocytoma, MYB- or MYBL1-altered (all previously diagnosed as diffuse astrocytoma, IDH-wildtype), 2 with diffuse midline glioma, H3 K27-altered (both previously diagnosed as diffuse midline glioma, H3 K27M-mutant), and 12 with diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype (all previously diagnosed as anaplastic astrocytoma, IDH-wildtype). This evidence concerns the gene IDH1 and diffuse midline glioma.