After adjustment for age, sex, history of hypertension, diabetes, stroke, prior mRS, SBP, GCS, hematoma location, hematoma volume, and hematoma expansion, the multivariable logistic regression analyses remained a significant association between FGF21 and unfavorable clinical outcomes [OR, 3.38 (95% CI, 1.41–8.06, p < 0.001); Table 2]. This evidence concerns the gene FGF21 and diabetes mellitus.