The age (66.0 years old IQR 57.0, 72.0), the prevalence of diabetes (30.7%), serum fibrinogen (2.93 g/L, IQR 2.48, 3.27), the Gensini score (24.0, IQR 14.3, 46.0), and serum NLRP1 (49.71 pg/ml, IQR 30.15, 80.21) levels of UA patients were significantly higher than those of non-UA patients (the age was 62.5 years old, IQR 53.0, 68.25; the prevalence rate of diabetes was 12%; the median serum fibrinogen was 2.67 g/L, IQR 2.29, 2.95; the median Gensini score was 5.0, IQR 2.9, 7.0; the median serum NLRP1 was 24.75 pg/ml, IQR 13.49, 41.95), with statistically significant differences (P < 0.05). The gene discussed is NLRP1; the disease is diabetes mellitus.