These anti-fibrotic activity results of curcumin and taurine are in concurrent with other studies on hepatic toxicity animal models induced liver fibrosis were treated with curcumin and taurine showed downregulated expression of TGFβ1 (Chen et al., 2018; Eshaghian et al., 2018; Yao et al., 2021; Mahmoudi et al., 2022). The gene discussed is TGFB1; the disease is Hepatic fibrosis.