When the prevalence of hepatitis B infection is compared to the prevalence of HBV infection (HBsAg positive or HBc positive or both are positive), the unvaccinated group showed a prevalence of 0.6%–16%, while the vaccinated group showed a prevalence of 0.3−8.5% (Whitford et al., 2018). This evidence concerns the gene KRT88P and hepatitis B virus infection.