NGFR and Alzheimer disease: Since in the late stages of AD monocyte-derived macrophages (MDM) infiltrate the brain parenchyma due to deficits in the blood brain barrier and the p75NTR is of known importance for macrophage activation (Williams et al., 2016; Bandoła et al., 2017; Ahn et al., 2018; Düsedau et al., 2019), we additionally assessed the activation of MDMs.