Some significant differences were shown in some variables, including age, sex, smoking status, Lp(a), HDL, TC, apolipoprotein A1 (Apo A1), total protein (TP), ALB, ALT, alkaline phosphatase (ALP), aspartate aminotransferase (AST), cholinesterase (ChE), creatinine (CREA), urea, glucose (GLU), total bilirubin (TBIL), direct bilirubin (DBIL), β2-MG, total bile acid (TBA), hypertension, hyperlipidemia (HLP), liver disease, and DM. The gene discussed is GPT; the disease is hyperkeratosis lenticularis perstans.