Some significant differences were shown in some variables, including age, sex, smoking status, Lp(a), HDL, TC, apolipoprotein A1 (Apo A1), total protein (TP), ALB, ALT, alkaline phosphatase (ALP), aspartate aminotransferase (AST), cholinesterase (ChE), creatinine (CREA), urea, glucose (GLU), total bilirubin (TBIL), direct bilirubin (DBIL), β2-MG, total bile acid (TBA), hypertension, hyperlipidemia (HLP), liver disease, and DM. This evidence concerns the gene APOA1 and hyperkeratosis lenticularis perstans.