Interestingly, Dgcr8 haploinsufficiency contributes to neurological, behavioral, and anatomical phenotypes of the 22q11 Deletion Syndrome (22q11DS), that encompasses DiGeorge syndrome, velo-cardio-facial syndrome and conotruncal anomaly face syndrome (Schofield et al., 2011). This evidence concerns the gene DGCR8 and 22q11.2 deletion syndrome.