The IL-17 family consists of different protein members, and the activation of IL-17A and IL-17F has been proven to induce IL-6 signaling, activation of the NF-кB inflammatory pathway, and the signaling pathway of the STAT3 transcription factor, which further leads to the activation of acute inflammation, antimicrobial and antifungal defense molecules and the development of different kinds of cancers (Alinejad et al. 2017). The gene discussed is IL17F; the disease is cancer.