In comparing the dose‐dependent protein suppression patterns of HF and DWN12088, we found that proteins with lower proline proportions, such as AMPKα and cyclin D1, were three times more sensitive to HF, whereas proteins with higher proline proportions, such as COL1A1 and ULK1, showed similar patterns (Fig 2A). Here, CCND1 is linked to hydrops fetalis.