C3 and infection: Given the higher fungal burdens (Figure S2, Supporting Information) and decreased complement activation observed in Sap2‐273L infections, we sought to investigate the correlation between C3a levels and fungal loads in the kidney following infection with Sap2‐273L, Sap2‐273V, or PBS (1 × 105 CFU, 100 μL/mouse) on day 2.